Most quality sparkplugs being made these days don't require the use of anti-seize, this came about because in the "olden days" there were numerous issues of plugs being seized in cylinder heads. People would end up breaking plugs trying to get them out and machine shops were kept busy extracting plugs. Plug manufacturers evolved to making plugs to address these issues. I've been wrenching on cars since '87, my FiST isn't my first rodeo and have always used anti-seize on components that are suspect to seize and cause angst down the line, exhaust manifold fasteners, turbocharger bolts, etc. (tons of threads about broken bolts and people having a hard time with fasteners).
I'm old school in using it sparingly on sparkplugs, we're talking about a small dab the size of 1 or 2 grains of rice. The sparkplug needs to be grounded to the cylinder head, so caking on anti-seize over every inch of tread is not good practice. I also use dielectric grease on the plugs for the coils. I've seen may coil plugs with heavy oxidation to cause problems, which dielectric grease would totally prevent. Dielectric grease is also a good lube for radiator hoses and turbo charge hoses. I prefer nickel over copper anti-seize for it's greater performance.