Do a search for threads started with my username. I've got write ups on my Revo S242, Peron 4 port aux fuel and GTX2860 turbo. There are dyno graphs for each mod that I have done and with different fuels. Should give you an example of what you can expect. Depending of the fuel you are going to run, most hybrids will need aux fuel to get past 300ish whp. With the current batch of hybrid turbo and aux fuel, I do believe the limit is 330ish whp. 93 octane pump gas makes a big difference too.
The S280 turbo is not a hybrid, since the turbine and compressor are not the same as the Borg Warner that a hybrid is based on. It's got a different turbine and compressor housing altogether. The same holds true with the X57 series from Pumaspeed. If I were to do it again, I'd go with the S280, because it should spool sooner than the GTX2860 and yield a lot more top end hp than a typical hybrid, but I don't think as much top end whp as a GTX2860. I have not seen any dyno numbers that show this, but with hearing on how the S280 and X57 are built, that's my assumption. Good luck.