You should mention what the car is being used for. A track car, Drag car, highway car will all see different levels of abuse on different parts of the car.
My best advice from someone who enjoys driving more than building, Prepare the rest of the car for big power and enjoy the car in stock power. Then when the rest of you chassis is ready, throw in the built engine. If you want to push as much power as possible and do the engine first, you are just going to run into roadblock after roadblock.