Honestly if you're planning on spending all that money on a built engine, I wouldn't stop at s280, I'd go after a g25-550 or 660, etc. With all the cams, and headwork, etc it'd probably spool a g25-550 damn near as fast as a S280, while having more power & top end.
Plus I want the engine to last. I want to keep reliability. That's why my tunes are so conservative.