Sure the name of the game is Volumetric Efficiency+Thermal Management = HorsePowwwwaaaaa. The easier the air goes in and out, the better off you are. I would not disagree that on some of these peoples cars there could be some areas where volumetric efficiency could be enhanced. But the general rule of thumb is that you never try to run more than double the boost pressure than what the wastegate spring is rated at. So people have been saying that the MRX is an 11lb spring, then 22psi will be roughly around its limits +/-. Since there is alot of variances of results based on the actuators diaphram size and spring size that can create slight variations in results.
Think of the wastegate as a door. If you put a 100 pound of weight behind the door keeping it closed, but only have 50 pounds of force pushing the door, the door wont open. But if you exceed 100 pounds of force against that door, then the door will open. No matter what electronic nannies you have to control the wastegate, if the exhaust force and or backpressure exceeds the springs strenght, it will open whether it wants to or not. I would assume the 11psi actuator used from Mountune was originally used for the fact that if there is ever an issue and the turbo starts only running wastegate pressure that it will never exceed safe limits that the engine and tuning can handle. If people start running a 22psi actuator, there will be no more safety cushion, so if there is ever a point the turbo runs on only wastegate pressure, the turbo may go into full overspeed chaos mode and hurt the engine, or itself.
Here is something from Gale Banks who is a really knowledgeable guy when it comes to turbochargers.
http://bankspower.com/techarticles/show/15-How-a-Turbo-Wastegate-Works