True, but that's also why I take the "recommended even on stock!" claims with a big grain of salt. Stock, factory-tuned overboost is capped at, what, 21psi for 10 seconds? Of course you can just let off the throttle to reset the timer and then slam it again to go right back into overboost. You're only going to be abusing that function on the track or by being an idiot on the highway, so needing colder plugs to compensate for boost/cylinder pressures on stock doesn't make much sense to me.
You're 100% correct about "real" tunes, though. That's where I can see it being viable.
As for comfort, well, misfires and engine hesitation make me awfully uncomfortable. Dunno 'bout you.